Skip the Hormone Pellets: Smarter HRT Options
- Stephanie Robison, APRN-CNP

- Nov 14
- 2 min read
Hormone replacement therapy (HRT) is a powerful tool for restoring balance and easing the symptoms of menopause, such as hot flashes, fatigue, low libido, and mood changes. However, not all delivery methods are created equal.

Understanding Hormone Pellets
While hormone pellets have gained popularity in recent years, they often come with more risks and less flexibility than other options, such as creams, patches, and injections. Pellets are small implants inserted under the skin that release hormones continuously for several months. Once placed, the dose cannot be adjusted, leaving little room for fine-tuning as your needs change or if side effects develop.
Why Flexibility Matters in Hormone Therapy
In contrast, other routes of hormone therapy allow for a more individualized and responsive approach, such as:
Transdermal creams and patches deliver hormones steadily through the skin and can be adjusted easily if symptoms or hormone levels change
Injections, though less common, offer flexibility in timing and dosing
These methods give both the patient and provider greater control, ensuring that therapy remains safe, effective, and tailored to your unique physiology.
The Safety Concerns with Hormone Pellets
Another key consideration is safety. Pellet therapy can sometimes cause excessively high hormone levels immediately after insertion, leading to:
Acne or unwanted hair growth
Mood swings or irritability
Breast tenderness
Cardiovascular concerns
Additionally, the insertion procedure itself carries small but real risks, such as infection, scarring, or pellet extrusion. Non-pellet methods, on the other hand, avoid these complications entirely and have been well studied for decades, giving providers clear, evidence-based guidance on dosing and monitoring.
Choosing a Personalized and Safe Approach
Ultimately, the best hormone replacement therapy is one that is personalized, monitored, and adaptable. While pellets may seem convenient, most patients benefit from a more flexible route that allows for ongoing communication and precise dose adjustments.
Hormone balance is not “one size fits all.” Safer, more customizable options, such as creams, patches, or injections, ensure your journey through menopause is managed with care, comfort, and confidence.
Take the First Step Toward Balanced Hormones
If you’ve been struggling with fatigue, weight changes, mood swings, or low libido, it might be time to explore a better approach to hormone therapy. At Onyx Weight Loss Clinic, we offer a free hormone introductory call to help you understand your options.



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